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Science

Clinically Tested & Doctor Recommended

Learn more about the doctors behind the TropolActive™ ingredients here.

How It Works

Learn about our active ingredients:

Elastatropin® (Tropoelastin)

Matrixyl - 3000®

Argireline®

Hyaluronic Acid (HA)

ProliSel®

 

Elastatropin® (Tropoelastin)

Elastatropin® is the most advanced skin care ingredient in the world. Tropoelastin was developed as part of a Defense Advanced Research Projects Agency (DARPA) competition on wound healing and tissue regeneration to help treat battlefield injuries.

Elastatropin®, the laboratory synthesized form of human tropoelastin, is the natural precursor of the human elastin in the skin. Elastatropin® helps restore the natural elastin content in the skin that is lost throughout the aging process, helping reduce the appearance and onset of wrinkles.

Tropoelastin’s natural composition allows it to move freely within the structure of the skin. Taking advantage of tropoelastin’s inherent ability to permeate the outer layer of skin, we have discovered a way to introduce a source of elastin from outside the body.

Using a complex chain of 600 amino acids in a patented molecular delivery system, our synthesized form of elastin Elastatropin® restores elastic properties to the skin. A wrinkle insurance against declining skin quality, the amino acids are part of the ingredients. The amino acids enable the chain, and the Elastatropin™, to penetrate the deepest parts of the topmost layer of skin. It enters into the outer skin layers, moving into the first active layer, the epidermis, converting into elastin then integrating itself into the skin matrix cross-linking with existing elastin and other proteins. This process, shown in the drawing below, expands the flexible backbone of the skin effectively reducing the appearance of existing lines while preventing the onset of new wrinkles and diminishing the signs of aging.

Like a wall, the outermost layer of skin, called the stratum corneum, protects the body from foreign molecules, serving as a barrier, even to some skincare ingredients. The stratum corneum also prevents water from leaving the body through the skin. The next layer, the epidermis, constantly regenerates itself as new skin forms in the innermost layer, the dermis.

The discovery of Elastatropin® and its effectiveness in fighting wrinkles introduces a comfortable, casual alternative to traditional age-defying procedures and ineffective creams and skincare products.

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Matrixyl - 3000®

Matrixyl 3000® is a combination of matrikines including Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide– 7.

Matrixyl 3000® promotes collagen production while stimulating fibroblast cells in the skin, enabling them to significantly reduce the appearance of wrinkles. Although fibroblasts never completely lose their ability to create more collagen, the levels dwindle with age and the skin dries out and wrinkles.

In clinical trials, Matrixyl 3000®, a key ingredient in Tropolactive™, achieved:

✓ 33% decrease in wrinkle density
✓ 23% decrease in the volume of wrinkles
✓ 20% decrease in the depth of wrinkles

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Argireline®

Argireline® is a unique new peptide, called Acetyl Hexapeptide-3, that both reduces existing facial wrinkles and is effective against the development of new wrinkles.

Studies with human volunteers show that Argireline delivers superior anti-wrinkle results, with the severity of wrinkles around the eyes decreased up to 17% after 15 days of treatment and up to 27% after 30 days of treatment. This represents a breakthrough in cosmetic science because of its remarkable speed in anti-wrinkle activity.

Argireline® also decreases the depth of facial wrinkles caused by the contraction of muscles from facial expressions, especially near the eyes and on the forehead.
Botox® targets the same wrinkles, but Argireline® is safer and less expensive.

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Hyaluronic Acid (HA)

Hyaluronic Acid is a complex carbohydrate that is distributed widely throughout the body in connective, epithelial, and neural tissues. One of the chief components of the Extracellular Matrix, HA contributes significantly to cell proliferation and migration and is a unique moisturizing agent because of its ability to retain water more effectively than any other natural substance.

By using one of the highest concentration of HA of any skin care product on the market, Tropolactive™ provides enhanced moisturizing effects and increases smoothness, softening and elasticity while decreasing facial wrinkles.

Hyaluronic acid is the active ingredient in the injectable filler, Restylane®. Restylane® is administered by plastic surgeons via transdermal injections. Each injection contains approximately 10mg of HA and costs $300-$500 dollars. The resulting balloon effect requires a refill about every 4 months. One injection is usually insufficient to address all lines and wrinkles in a typical face so that the annual cost of Restylane® injections can be in the thousands of dollars. At the end of the treatment regimen, you can only look forward to starting again and spending thousands more.

One container of Tropolactive-S™ contains 3500mg of HA that is the equivalent of over 350 Restylane® injections. Over a two month period that is the same amount of HA as you would get if you got a shot every other day.

Daily applications of HA results in a gradual restoration of HA levels to permanently improve hydration and skin lubrication. Recent scientific studies have proven that the cumulative effect of regular HA applications is more important to long-term skin health than the short term balloon effect.

Why spend thousands to the get benefit of HA when it is available in Tropolactive-S™ for next to nothing?

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ProliSel®

Only Tropolactive™ branded products contain ProliSel®, a formulation that acts as both an antioxidant and anti-carcinogen.

ProliSel® contains a biologically active form of selenium that is extremely effective in preventing oxidation of the skin.

Additionally, ProliSel® contains other skincare ingredients to slow down the process of aging by protecting against the effects of photooxidation and photodamage. Only Tropolactive® contains the unique combination of Oxidation Protective compounds found in ProliSel®.

ProliSel® consists of a mixture of amino acids with a powerful ability to reduce damage caused by exposure to the sun and environmental insults to the skin. ProliSel® contains L-selenomethionine, a highly bioavailable selenium source, as well as amino acids L-Proline and L-Cysteine.

Scientific studies have proven that all three of these vital amino acids significantly reduce cell damage and programmed cell death caused by exposure to UV light or Reactive Oxygen Species.

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Learn more about the doctors behind the Tropolactive™ ingredients here.